VPRIV DOSING CALCULATOR
You understand your patients and the various stages they’ll experience in their individual journeys. We understand your needs in supporting your patients on their journey. Our goal is to help make sure you’re not just ready, you’re VPRIV Ready.
DOSING CALCULATION
VPRIV dosing
- VPRIV is administered as a 60-minute intravenous (IV) infusion once every other week under the supervision of a healthcare professional1
- Always refer to VPRIV’s Prescribing Information, which contains complete dosing and administration
information, before administering VPRIV
- Dosage adjustments may be made on an individual basis based on the achievement and maintenance of therapeutic goals1
- VPRIV is dosed according to body weight1
VPRIV dosing calculator
Precise dosing requires patient’s exact weight and an individual calculation by the healthcare professional.
Obtain patient’s weight1
Please enter patient weight in:
Patient Weight
=
kg
Dosage of VPRIV Required
=
U
Number of Vials Needed
=
vials
Obtain patient’s weight1
Calculate the dosage of VPRIV required*:
Patient weight (kg) × 60 U/kg
Calculate the number of vials needed†:
Required VPRIV dosage ÷ 400
Use the exact unit of the required VPRIV dosage—do not round up to the nearest full vial.1
Dispose of unused product.
Patient’s weight = 21 kg
21 kg × 60 U/kg of VPRIV =
1,260 U
1,260 ÷ 400 = 3.15 vials needed
(4 vials are needed to extract 1,260 U of VPRIV)
*Recommended dose of VPRIV is 60 U/kg patient body weight administered once every other week as an
IV infusion.1 This will change if pounds are used in the calculation instead.
†1 vial of VPRIV = 400 Units (U)1
PATIENT ASSESSMENT
As with any infusion or medical procedure, it is important to assess your patient’s current condition and review their medical history, including any ERT for type 1 Gaucher disease.1 Initiate VPRIV treatment in a healthcare setting with appropriate medical monitoring and support measures, including access to cardiopulmonary resuscitation equipment.1 Administration of VPRIV should be supervised by a healthcare provider knowledgeable in the management of hypersensitivity reactions including anaphylaxis.1
Check preinfusion vital signs and labs, if required per facility infusion protocol1
Review previous infusion notes, if any, to determine if the patient has had infusion reactions to an ERT and to assess any changes since the last visit1
Consider pre-treatment with antihistamines and/or corticosteroids in patients who exhibited symptoms of hypersensitivity associated with prior velaglucerase alfa product infusions1
Notify the patient’s treating physician if the infusion cannot be administered1
