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VPRIV ADMINISTRATION

You understand your patients and the various stages they’ll experience in their individual journeys. We understand your needs in supporting your patients on their journey. Our goal is to help make sure you’re not just ready, you’re VPRIV Ready.
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VPRIV ADMINISTRATION
  • VPRIV should be administered under the supervision of a healthcare professional1
  • Diluted VPRIV should be administered through an in-line low protein-binding 0.2 or 0.22 µm filter. VPRIV should not be infused with other products in the same infusion tubing. The compatibility of VPRIV in a solution with other products has not been evaluated1
1

Attach IV tubing to the bag of VPRIV solution. IV tubing should have an in-line filter in place.1

Attaching IV tube to bag of VPRIV
2

Use normal saline to prime tubing and expel all air.

Injecting saline to expel air
3

Set the infusion to administer at the rate prescribed. A 60-minute infusion is recommended.1

Timer for 60 minute infusion
4

Select the IV infusion site; this will vary by patient and may include: antecubital, wrist, or hand veins, or a central venous catheter. Follow your facility’s policies for IV insertion, medication infusion, and disposal of biohazardous waste.

Hand/wrist (infusion site)
5

Begin VPRIV therapy infusion with the flow-regulating device or IV pump. Monitor the patient regularly. If anaphylactic or other acute reactions occur, discontinue VPRIV immediately and immediately initiate appropriate medical treatment, including use of epinephrine.1

Please see Boxed Warning for hypersensitivity reactions, including anaphylaxis, and Section 5.1 of the Warnings and Precautions section of the Prescribing Information for important information on hypersensitivity reactions.
Dosing and infusion guide

IMPORTANT SAFETY INFORMATION

WARNING: HYPERSENSITIVITY REACTIONS INCLUDING ANAPHYLAXIS

Patients treated with enzyme replacement therapies have experienced life-threatening hypersensitivity reactions, including anaphylaxis. Anaphylaxis has occurred during the early course of enzyme replacement therapy and after extended duration of therapy.

Initiate VPRIV in a healthcare setting with appropriate medical monitoring and support measures, including access to cardiopulmonary resuscitation equipment.