VPRIV CLINICAL PROGRAM OVERVIEW

VPRIV was evaluated in 99 patients (aged ≥ 4 years) across three initial clinical trials. Some of these patients were then enrolled into one phase III, open-label, long-term extension trial conducted in adult and pediatric patients (n=93; patients aged ≥ 4 years).1

up arrowClick  through the sections below to learn more about VPRIV’s clinical trials.

TREATMENT-NAÏVE

12-MONTH
PARALLEL-DOSE STUDY3


STUDY 032

9-MONTH
HEAD-TO-HEAD (NON-INFERIORITY) STUDY4

STUDY 039

5-YEAR LONG-TERM EXTENSION STUDY6

STUDY 044

HUGHES ET AL. PUBLICATION

TREATMENT-EXPERIENCED

12-MONTH
SWITCH STUDY5


STUDY 034

5-YEAR LONG-TERM EXTENSION STUDY7

STUDY 044

ELSTEIN ET AL. PUBLICATION

Treatment-naïve: patients who had not received disease-specific treatment within the 30 months prior to starting VPRIV.6

Treatment-experienced: patients previously treated with imiglucerase for a minimum of 30 consecutive months prior to switching to VPRIV.5